In response to the Haiti earthquake, there are many opportunities to donate and help. Over the years, as needs like this arise, I have given to FAIR (Fellowship Agency for International Relief). One of the things I like about them is that they partner with organizations that are already involved in the area. In Haiti they are partnering with Emmanuel International to distribute aid through local churches. Bonus: Until February 12th, every dollar given through FAIR will be matched by the Canadian government.
Update: David Daniels provides a recommendation for Emmanuel International.